Project description
SAICM USEtox

The project's aim is to further expand the scientific consensus model USEtox to address near-field exposure for building products and plastic toys, drawing on expertise and data on Chemicals of Concern (CoC) and related alternatives from the scientific community as well as building material and toy sector supply chain information.

SAICM USEtox

Background & project objective

This Global Environment Facility (GEF) project focuses on the objectives to accelerate adoption of national and value chain initiatives to control Emerging Policy Issues (EPIs), and contribute to the 2020 SAICM goal and 2030 Agenda for Sustainable Development.

SAICM USEtox

The project helps to further expanding the global reference model USEtox to address near-field exposure for building products and plastic toys, drawing on expertise and data on Chemicals of Concern (CoC) and related alternatives from the scientific community as well as building material and toy sector supply chain information. Ultimately, this will help authorities and other decision makers and value chain actors in the building products and toys sectors tracking and managing chemicals of concern (CoC) in their products.

SAICM USEtox
SAICM USEtox

Project output

Main project output are several published and upcoming scientific open access articles listed in below table.

Document titleDownload file
Fantke, P., Huang, L., Overcash, M., Griffing, E., Jolliet, O., 2020. Life cycle based alternatives assessment (LCAA) for chemical substitution. Green Chemistry 22: 6008-6024.https://doi.org/10.1039/D0GC01544J
Aurisano, N., Huang, L., Mila i Canals, L., Jolliet, O., Fantke, P., 2021. Chemicals of concern in plastic toys. Environment International 146: 106194.https://doi.org/10.1016/j.envint.2020.106194
Fantke, P., Chiu, W.A., Aylward, L., Judson, R., Huang, L., Jang, S., Gouin, T., Rhomberg, L., Aurisano, N., McKone, T., Jolliet, O., 2021. Exposure and toxicity characterization of chemical emissions and chemicals in products: Global recommendations and implementation in USEtox. The International Journal of Life Cycle Assessment 26: 899-915.https://doi.org/10.1007/s11367-021-01889-y
Jolliet, O., Huang, L., Hou, P., Fantke, P., 2021. High throughput risk and impact screening of chemicals in consumer products. Risk Analysis 41: 627-644.https://doi.org/10.1111/risa.13604
Aurisano, N., Fantke, P., Huang, L., Jolliet, O., 2022. Estimating mouthing exposure to chemicals in children’s products. Journal Of Exposure Science And Environmental Epidemiology 32: 94-102.https://doi.org/10.1038/s41370-021-00354-0
Huang, L., Fantke, P., Ritscher, A., Jolliet, O., 2022. Chemicals of concern in building materials: A high-throughput screening. Journal of Hazardous Materials 424: 127574.https://doi.org/10.1016/j.jhazmat.2021.127574
Aurisano, N., Jolliet, O., Chiu, W.A., Judson, R., Jang, S., Unnikrishnan, A., Kosnik, M.B., Fantke, P., 2023. Probabilistic points of departure and reference doses for characterizing human non-cancer and developmental/reproductive effects for 10,145 chemicals. Environmental Health Perspectives 131: 037016.https://doi.org/10.1289/EHP11524
Owsianiak, M., Hauschild, M.Z., Posthuma, L., Saouter, E., Vijver, M.G., Backhaus, T., Douziech, M., Schlekat, T., Fantke, P., 2023. Ecotoxicity characterization of chemicals: Global recommendations and implementation in USEtox. Chemosphere 310: 136807.https://doi.org/10.1016/j.chemosphere.2022.136807
Aurisano, N., Fantke, P., Chiu, W.A., Judson, R.S., Jang, S., Unnikrishnan, A., Jolliet, O., 2024. Probabilistic reference and 10% effect concentrations for characterizing inhalation non-cancer and developmental\/reproductive effects for 2,160 substances. Environmental Science and Technology 58: 8278-8288.https://doi.org/10.1021/acs.est.4c00207
Huang, L., Aurisano, N., Fantke, P., Dissanayake, A., Edirisinghe, L.G.L.M., Jolliet, O., 2024. Near-field exposures and human health impacts for organic chemicals in interior paints: A high-throughput screening. Journal of Hazardous Materials 465: 133145.https://doi.org/10.1016/j.jhazmat.2023.133145
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